[Blueboard] Seminar on "The Future is Natural" by Dr. Fabian Dayrit July 4, 2013 4:30-6:00

Gina B. Mamauag gmamauag at ateneo.edu
Wed Jul 3 08:49:18 PHT 2013

The Department of Chemistry, invites you to the seminar of Dr. Fabian
Dayrit entitled "The Future is Natural" on July 4, 2013 4:30-6:00 at C109,
Schmitt Hall.


The Future is Natural
Dr. Fabian M. Dayrit
Department of Chemistry, Ateneo de Manila University
Despite advances in medical therapeutics, Nature still harbors the best
Virgin coconut oil (VCO) and Alzheimer’s Disease (AD). AD is a complex
brain disease which is associated with the formation of beta-amyloid
plaques and hyperphosphorylated tau tangles in the brain. However, despite
the large investments in the development of drugs against AD, no successful
drug has been found. In 2009, the US FDA approved Axona®, a “medical food”
to manage AD. The active ingredient of Axona® is tricaprylidene, a medium
chain triglyceride (MCT). The action of MCT is based on the hypothesis that
ketone bodies, which are produced by MCTs provides energy for the brain
which halts the progression of AD. This project seeks to study the effect
of VCO on AD using rats with induced AD.
Medium-chain triglycerides from Coconut oil 
Ketone bodies: -hydroxybutyrate + -ketobutyrate
Standardization and Chemical Profiling of Medicinal Plants. Among the
important requirements of Good Manufacturing Practice (GMP) for medicine
plant products are standardization and chemical profiling. This requires
the identification and quantitative determination of phytochemicals and
measurement of the variation of these compounds in plants produced around
the country under varying conditions.

​Thank you.​

*Gina Mamauag-Buan
*Chemistry Department
*Ateneo de Manila University*
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